SEPARATION OF GEOMETRIC ISOMER OF TRIAZOLYL STYRYL KETONE DERIVATIVE

PURPOSE:To obtain the E-isomer of the titled compound useful as a fungicide or intermediate of fungicide, herbicide, etc., with simple operation, in high purity, from the mixture of geometric isomers of triazolyl styryl ketone derivative, by converting the mixture to sulfates in a solvent,and separating the objective isomer. CONSTITUTION:A mixture of geometric isomers of the triazolyl styryl ketone derivative of formula is made to react with sulfuric acid in a solvent, preferably an aprotic organic solvent such as benzene, toluene, chloroform, etc. to precipitate the sulfate of the E-isomer of the above derivative in the form of crystal. The sulfate is separated and decomposed to obtain the E-isomer of the triazolyl styryl ketone derivative. The concentration of the sulfuric acid is usually >=40%, perferably 90-98%, and the amount of the acid is usually 0.5-3mol, preferably 0.95-1.2mol in terms of pure sulfuric acid based on 1mol of the E-isomer in the E/Z mixture.