ALPHA-SUBSTITUTED UREIDOBENZYLPENICILLANIC ACID

NEW MATERIAL:A compound of formulaI[R is H or OH; X is n-5C alkyl; Y is group of -(OR )m (R is H, 1-4C lower alkyl, 2-4C lower alkanoyl, etc; m is 1, 2 or 3), group -CN, -COOR (R is H or 1-4C lower alkyl), etc.; n is 2 when Y is -(OR )m, and 1 when Y is another group]and a pharmacologically acceptab...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	KUROKI TOSHIO, SHINOZAKI TEIZOU, MATSUNAGA ISAO, OOI NOBUHIRO, NOFUJI TAKAO, MORO KANJI, NEHASHI TOSHIYUKI, OKAZAKI HIROSHI, SHINDOU MINORU, MATSUMOTO MASAHIKO, ENDOU HISAO, KOJIMA KANA, AOKI BUNYA, KIMURA TAKAO, OGAWA HARUKI, HARADA YUUSUKE
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	NEW MATERIAL:A compound of formulaI[R is H or OH; X is n-5C alkyl; Y is group of -(OR )m (R is H, 1-4C lower alkyl, 2-4C lower alkanoyl, etc; m is 1, 2 or 3), group -CN, -COOR (R is H or 1-4C lower alkyl), etc.; n is 2 when Y is -(OR )m, and 1 when Y is another group]and a pharmacologically acceptable salt thereof. EXAMPLE:6-{D(-)-alpha-[3-(3,4-Dihydroxybenzoyl)-3-(3-hydroxypropyl)-1- ureido]- alpha-phenylacetamide}penicillanic acid. USE:An antimicrobial agent capable of exhibiting the activity in the living body particularly on some kinds of microorganisms belonging to the genus Pseudomonas. PROCESS:A novel compound of formula II (R is H, OH, etc.; R is OH, etc.) or a reactive derivative, e.g. pivalic acid or trichloroacetic acid, is reacted with a compound of formula III (R is H or protecting group) or a reactive derivative thereof, and the protecting group is then removed to give the aimed compound of formulaI.