OPHTHALMIC SOLUTION CONTAINING NON-STEROID ANTIPHLOGISTIC AGENT AS MAIN COMPONENT

PURPOSE:To prepare a remedy for ophthalmia giving low irritation to the ocular mucous membrane, in the form of ophthalmic solution, by using ketoprofen or its salt as a main component. CONSTITUTION:An ophthalmic solution having remarkably reduced irritativity to the ocular-mucous membrane is prepare...

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Bibliographische Detailangaben
Hauptverfasser: YAMAUCHI HIDEYASU, ISO TADASHI, IWATANI TERUMICHI, IWAO JIYUNICHI
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To prepare a remedy for ophthalmia giving low irritation to the ocular mucous membrane, in the form of ophthalmic solution, by using ketoprofen or its salt as a main component. CONSTITUTION:An ophthalmic solution having remarkably reduced irritativity to the ocular-mucous membrane is prepared by using ketoprofen or its salt as a main component, and preferably adding a basic amino acid (e.g. arginine, lysine, ornithine, histidine, etc.) to the solution. The agent does not exhibit the side effects such as stimulation of gastric mucosa caused by the general administration e.g. oral administration, and gives high local concentration of the active component.