ALKYL- AND CYCLOALKYL-SUBSTITUTED 2-(2-(2- HYDROXY-3-T-BUTYLAMINO-PROPOXY)-5-ACYLAMINO- PHENYL)-1,3,4-OXADIAZOLE, MANUFACTURE AND DRUG CONTAINING SAME

ALKYL- AND CYCLOALKYL-SUBSTITUTED 2-(2-(2- HYDROXY-3-T-BUTYLAMINO-PROPOXY)-5-ACYLAMINO- PHENYL)-1,3,4-OXADIAZOLE, MANUFACTURE AND DRUG CONTAINING SAME

A compound of the formula (I) wherein R is a straight or branched chain alkyl group having 1 to 17 carbon atoms or a cycloalkyl group having 3 to 6 carbon atoms; as well as the physiologically acceptable acid addition salts thereof. A method of production of the compounds, pharmaceutical composition...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: EERITSUHI KOONEN
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A compound of the formula (I) wherein R is a straight or branched chain alkyl group having 1 to 17 carbon atoms or a cycloalkyl group having 3 to 6 carbon atoms; as well as the physiologically acceptable acid addition salts thereof. A method of production of the compounds, pharmaceutical compositions containing them, and methods of use are also disclosed. The compounds of the present invention are useful in the treatment of angina pectoris, hypertension, and certain forms of arrhythmia.