PYRIDAZINONE DERIVATIVE

NEW MATERIAL:The compound of formula I (m is integer 2-6). EXAMPLE:2-(4-Aminobutyl)-6-phenyl-3(2H)pridazinone. USE:Remedy and preventive for hyperacidity, gastric ulcer, and duodenal ulcer, and their synthetic intermediates. PROCESS:The compound of formula I can be prepared by, e.g. the Gabriel reac...

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Bibliographische Detailangaben
Hauptverfasser: SHIMAMURA HIROSHI, YAMADA TOSHIHIRO, NOBUHARA YOUICHI
Format: Patent
Sprache:eng
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Zusammenfassung:NEW MATERIAL:The compound of formula I (m is integer 2-6). EXAMPLE:2-(4-Aminobutyl)-6-phenyl-3(2H)pridazinone. USE:Remedy and preventive for hyperacidity, gastric ulcer, and duodenal ulcer, and their synthetic intermediates. PROCESS:The compound of formula I can be prepared by, e.g. the Gabriel reaction of the phthalimide derivative of formula II with hybrazine hydrate, or the treatment of the bromine derivative having an eliminable group which can be undergo the substitution reaction, e.g. the compound of formula III, with aqueous ammonia.