NOVEL NUCLEOTIDE AND ITS PREPARATION

NEW MATERIAL:A compound shown by the formulaI(A is deoxyadenosyl residue; C is deoxycytidyl residue; T is thymidyl residue; P is a group shown by the formula). USE:A material for preparing a physiologically active substance having a contraction action on the smooth muscle of cholecyst and secretion...

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Hauptverfasser: TACHIBANA SHINROU, WAKABAYASHI TOSHIAKI
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creator TACHIBANA SHINROU
WAKABAYASHI TOSHIAKI
description NEW MATERIAL:A compound shown by the formulaI(A is deoxyadenosyl residue; C is deoxycytidyl residue; T is thymidyl residue; P is a group shown by the formula). USE:A material for preparing a physiologically active substance having a contraction action on the smooth muscle of cholecyst and secretion action on the pancreatic enzyme by the technique of genetic engineering. PROCESS:A compound shown by the formula III (A deg. is N-benzoyldeoxyadenosyl residue; C deg. is N-benzoyldeoxycytidyl residue; P is a group shown by the formula IV; DMT is dimethoxytrityl which protects 5'-OH of nucleoside) is condensed with a compound shown by the formula V (Bz is benzoyl which protects 3'-OH of nucleoside), and all the protecting groups are eliminated, to give dodecanucleotide shown by the formulaI. The condensation is carried out in the presence of a condensation agent obtained by combining a group of mesitylene sulfonyltriazole, etc. with a group of 1-methylimidazole, etc.
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USE:A material for preparing a physiologically active substance having a contraction action on the smooth muscle of cholecyst and secretion action on the pancreatic enzyme by the technique of genetic engineering. PROCESS:A compound shown by the formula III (A deg. is N-benzoyldeoxyadenosyl residue; C deg. is N-benzoyldeoxycytidyl residue; P is a group shown by the formula IV; DMT is dimethoxytrityl which protects 5'-OH of nucleoside) is condensed with a compound shown by the formula V (Bz is benzoyl which protects 3'-OH of nucleoside), and all the protecting groups are eliminated, to give dodecanucleotide shown by the formulaI. The condensation is carried out in the presence of a condensation agent obtained by combining a group of mesitylene sulfonyltriazole, etc. with a group of 1-methylimidazole, etc.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DERIVATIVES THEREOF ; ENZYMOLOGY ; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC ; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; SUGARS ; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS ; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE ; VINEGAR ; WINE</subject><creationdate>1982</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19821218&amp;DB=EPODOC&amp;CC=JP&amp;NR=S57206697A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19821218&amp;DB=EPODOC&amp;CC=JP&amp;NR=S57206697A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TACHIBANA SHINROU</creatorcontrib><creatorcontrib>WAKABAYASHI TOSHIAKI</creatorcontrib><title>NOVEL NUCLEOTIDE AND ITS PREPARATION</title><description>NEW MATERIAL:A compound shown by the formulaI(A is deoxyadenosyl residue; C is deoxycytidyl residue; T is thymidyl residue; P is a group shown by the formula). 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
VINEGAR
WINE
title NOVEL NUCLEOTIDE AND ITS PREPARATION
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