NOVEL 5-SUBSTITUTED-2-((N-MORPHOLINO)-N-NITROSOAMINO- METHYL)OXADIAZOLE DERIVATIVE AND PREVENTING AGENT FOR THROMBOSIS CONTAINING THE SAME AS PRINCIPAL CONSTITUENT

NEW MATERIAL:A 5-substituted-2-[( N-morpholino )-N-nitrosoamino-methyl]-1,3, 4-oxadiazole derivative expressed by formulaI(R is 1-3C alkyl, phenyl or p- dimethylaminophenyl). EXAMPLE:5-Methyl-2-[(N-morpholino)-N-nitrosoamino-methyl]-1,3,4-oxadia zole. USE:A preventing agent for thrombosis. PROCESS:A...

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Bibliographische Detailangaben
Hauptverfasser:	ASAI HIROMOTO, SUZUKI TOMOO, SUENAGA EIICHI, HIDAKA HIROYOSHI, BAN MASATOSHI, KUWAYAMA AKIJI, KONDOU YASUAKI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	NEW MATERIAL:A 5-substituted-2-[( N-morpholino )-N-nitrosoamino-methyl]-1,3, 4-oxadiazole derivative expressed by formulaI(R is 1-3C alkyl, phenyl or p- dimethylaminophenyl). EXAMPLE:5-Methyl-2-[(N-morpholino)-N-nitrosoamino-methyl]-1,3,4-oxadia zole. USE:A preventing agent for thrombosis. PROCESS:A 5-substituted-2-[(N-morpholinoamino)-methyl]oxadiazole expressed by formula II is nitrosated with NaNO2 to give the compound expressed by formulaI.