PHENYLPIPERAZINE DERIVATIVES OF HETARYLPHENOL AND HETARYLANILINE, MANUFACTURE AND MEDICINE

PHENYLPIPERAZINE DERIVATIVES OF HETARYLPHENOL AND HETARYLANILINE, MANUFACTURE AND MEDICINE

Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstitu...

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Bibliographische Detailangaben
Hauptverfasser: GERUTO SHIYUTAINAA, UORUFUGANGU ROORU, HANSU PEETAA HOFUMAN, HAARARUTO WAIFUENBATSUHA, HORUSUTO KURAISUKOTSUTO, DEIITAA RENKE, PEETAA TSUEE CHIIME, HANSUUYURUGEN TETSUSHIENDORUFU, YOOZEFU GURIISU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.