NOVEL BENZENECARBOXYAMIDE DERIVATIVES, MANUFACTURE AND MEDICINAL COMPOSITION

NOVEL BENZENECARBOXYAMIDE DERIVATIVES, MANUFACTURE AND MEDICINAL COMPOSITION

Compounds of the general formula: and non-toxic physiologically acceptable salts thereof, in which R1 is a halogen atom or a group NR2R3; R2 and R3, which may be the same or different, are hydrogen or (C1-C6) straight or branched chain alkyl or R2 and R3 may, together with the nitrogen atom, form a...

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Hauptverfasser: AREKUSANDAA UIRIAMU OTSUKUSUFUOODO, IAN HARORUDO KOUTESU
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of the general formula: and non-toxic physiologically acceptable salts thereof, in which R1 is a halogen atom or a group NR2R3; R2 and R3, which may be the same or different, are hydrogen or (C1-C6) straight or branched chain alkyl or R2 and R3 may, together with the nitrogen atom, form a 5 or 6 membered heterocyclic ring which may contain a further hetero atom selected from O, N or S; or R2 may be hydrogen and R3 may by group R4CO or R4SO2 where R4 is hydrogen or alkyl (C1-4); R5 is hydrogen or one or more halogen atoms or hydroxy or alkoxy (C1-4) groups; and X is CH2, O or a group NR6 where R6 is hydrogen or alkyl (C1-4). These compounds block beta -adrenoreceptors.