AROMAALIPHATIC DIHALOGENIDE AND PROCESS FOR PREPARATION THEREOF

Compounds of the formula wherein R1 and R2 are the same or different and are F, Cl or Br; Q is -CH(CH3)-CH2-, -C(OH) (CH3)-CH2- or -C(CH3) =CH-; Y is COOH, COOR3, CH2OH or CH2OAc; N IS 0 OR 1; R3 is alkyl or aryl of up to 8 carbon atoms or C6H4NHCOCH3; and Ac is acyl of 1-8 carbon atoms; AND PHYSIOL...

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Bibliographische Detailangaben
Hauptverfasser: HANSU ADORUFU KUURUMAIYAA, DEIITAA ORUTSU, ARUBUREHITO BIRUTSU, YOAHIMU GANTE, EERITSUHI SHIYAHATO
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds of the formula wherein R1 and R2 are the same or different and are F, Cl or Br; Q is -CH(CH3)-CH2-, -C(OH) (CH3)-CH2- or -C(CH3) =CH-; Y is COOH, COOR3, CH2OH or CH2OAc; N IS 0 OR 1; R3 is alkyl or aryl of up to 8 carbon atoms or C6H4NHCOCH3; and Ac is acyl of 1-8 carbon atoms; AND PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF, ARE ANTI-INFLAMMATORY AGENTS, WHICH CAN BE MADE FROM COMPOUNDS OF THE FORMULA Z - X, wherein Z is AND X can be converted to -Q-Y.