ALKYNE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF

Alkyne compounds of the formula wherein R1 is H, alkyl of up to 4 carbon atoms or phenyl; R2 is H, aliphatic acyl of up to 6 carbon atoms or aroyl of up to 11 carbon atoms; R3 and R4 are H, F, Cl or Br and n is 0 or 1, and physiologicaly acceptable metals salts thereof, have antiinflammatory activit...

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Bibliographische Detailangaben
Hauptverfasser:	HANSU ADORUFU KUURUMAIAA, DEIITAA ORUTSU EERITSUHI SHIYAHATO, YOAHIMU GANTE, ARUBUREHITO BUIRUTSU
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Alkyne compounds of the formula wherein R1 is H, alkyl of up to 4 carbon atoms or phenyl; R2 is H, aliphatic acyl of up to 6 carbon atoms or aroyl of up to 11 carbon atoms; R3 and R4 are H, F, Cl or Br and n is 0 or 1, and physiologicaly acceptable metals salts thereof, have antiinflammatory activity. These compounds can be made from compounds of the formula wherein Q is a functionally-modified hydroxy and R1, R3, R4 and n are as above by treatment with a solvolyzing agent.