HORUMIRUKINO DATSURIHO

The masking N-formyl group of an N-formyl-amino acid ester or N-formyl-peptide ester is removed without major side reactions when the ester is reacted in an inert liquid medium with hydroxylamine of which at least 70% is present in the form of a salt with a strong acid, the remainder, if any, being...

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Bibliographische Detailangaben
Hauptverfasser: TAKEMOTO TADASHI, ARYOSHI YASUO, KAKIZAKI FUSAYOSHI, NODA ICHIRO
Format: Patent
Sprache:eng
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Zusammenfassung:The masking N-formyl group of an N-formyl-amino acid ester or N-formyl-peptide ester is removed without major side reactions when the ester is reacted in an inert liquid medium with hydroxylamine of which at least 70% is present in the form of a salt with a strong acid, the remainder, if any, being present as the free base or the salt of a weak acid.