THERAPEUTIC AGENT FOR DIABETES

PROBLEM TO BE SOLVED: To obtain a therapeutic agent having a low side effect, low toxicity and high safety by using dephostatin as an active component. SOLUTION: The objective therapeutic agent is produced by including 0.01-100 wt.% of dephostatin of the formula as an active component in the agent....

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Bibliographische Detailangaben
Hauptverfasser: TAKEUCHI TOMIO, UMEZAWA KAZUO, SAWA TSUTOMU, KITAHARA MIKIRO, YAMASHITA TAKASHI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To obtain a therapeutic agent having a low side effect, low toxicity and high safety by using dephostatin as an active component. SOLUTION: The objective therapeutic agent is produced by including 0.01-100 wt.% of dephostatin of the formula as an active component in the agent. The daily administration rate for adult is usually 0.01-1,000 mg/kg in one or divided doses. It can be used in the form of peroral agent, injection, suppository, poultice, etc., and peroral agent is preferable from the viewpoint of the physical load on the patient. It has remarkable suppressing effect on the release of free fatty acid from cultured fat cell by epinephrine stimulation without accompanying cell damage.