NEW COMPOUND

PROBLEM TO BE SOLVED: To obtain a polynucleotide newly isolated which possesses high homology over the whole length to the nucleic acid that codes for the polypeptide having a specific amino acid sequence and is useful for treatment and diagnosis assay for disorder relevant to ingestion, neurologica...

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1. Verfasser: SOUTHAN CHRISTOPHER DONALD
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creator SOUTHAN CHRISTOPHER DONALD
description PROBLEM TO BE SOLVED: To obtain a polynucleotide newly isolated which possesses high homology over the whole length to the nucleic acid that codes for the polypeptide having a specific amino acid sequence and is useful for treatment and diagnosis assay for disorder relevant to ingestion, neurological disease, cancer and ache. SOLUTION: This newly isolated polynucleotide contains the nucleotide sequence having at least 85% of homology over the whole length to the nucleotide sequence that codes for the polypeptide of the formula or the nucleotide sequence complementary to the isolated polynucleotide and is useful in the treatment or diagnosis for disorder relevant to ingestion, e.g. obesity, cibophobia, blimia or the like, asthma, Parkinson disease, acute heart failure, hypertension, urinary retention, osteoporosis, angina pectoris, myocardial infarction, ulcer, allergy, psychosis, neurological disease, cancer or ache. This polynucleotide is obtained as the pancreatic polypeptide gene by the use of normal cloning and screening from cDNA library arising from human fetus splenic cells by means of expression sequence tag(EST) analysis.
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SOLUTION: This newly isolated polynucleotide contains the nucleotide sequence having at least 85% of homology over the whole length to the nucleotide sequence that codes for the polypeptide of the formula or the nucleotide sequence complementary to the isolated polynucleotide and is useful in the treatment or diagnosis for disorder relevant to ingestion, e.g. obesity, cibophobia, blimia or the like, asthma, Parkinson disease, acute heart failure, hypertension, urinary retention, osteoporosis, angina pectoris, myocardial infarction, ulcer, allergy, psychosis, neurological disease, cancer or ache. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title NEW COMPOUND
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