ANTIPHLOGISTIC-SEDATIVE MEDICINE FOR EXTERNAL USE
PROBLEM TO BE SOLVED: To obtain the subject medicine maintaining the percutaneous absorption property of indomethacin and improving the stability of indomethacin by including α-type crystal indomethacin. SOLUTION: This antiphlogistic-sedative medicine for external use contains indomethacin existing...
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| creator | OTSUKI TOMOHIRO YOSHINO YOSHIKO KIUCHI CHIKAKO |
| description | PROBLEM TO BE SOLVED: To obtain the subject medicine maintaining the percutaneous absorption property of indomethacin and improving the stability of indomethacin by including α-type crystal indomethacin. SOLUTION: This antiphlogistic-sedative medicine for external use contains indomethacin existing as α-type crystal in a base agent, for example, by a method comprising mixing an indomethacin suspension (prepared by homogeneously dispersing indomethacin, a water-soluble polymer, a moisturizing agent, a surfactant, an antiseptic, etc., in a solvent) with a water-soluble gel preferably in a weight ratio of 70:30 to 95:5. The indomethacin is preferably added usually in an amount of 1-40 wt.% to the above-described suspension or usually in an amount of 0.1-2 wt.% to the medicine. The water-soluble polymer is preferably added usually in an amount of 3-30 wt.% to the medicine. |
| format | Patent |
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SOLUTION: This antiphlogistic-sedative medicine for external use contains indomethacin existing as α-type crystal in a base agent, for example, by a method comprising mixing an indomethacin suspension (prepared by homogeneously dispersing indomethacin, a water-soluble polymer, a moisturizing agent, a surfactant, an antiseptic, etc., in a solvent) with a water-soluble gel preferably in a weight ratio of 70:30 to 95:5. The indomethacin is preferably added usually in an amount of 1-40 wt.% to the above-described suspension or usually in an amount of 0.1-2 wt.% to the medicine. The water-soluble polymer is preferably added usually in an amount of 3-30 wt.% to the medicine.</description><edition>6</edition><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990629&DB=EPODOC&CC=JP&NR=H11171768A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990629&DB=EPODOC&CC=JP&NR=H11171768A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OTSUKI TOMOHIRO</creatorcontrib><creatorcontrib>YOSHINO YOSHIKO</creatorcontrib><creatorcontrib>KIUCHI CHIKAKO</creatorcontrib><title>ANTIPHLOGISTIC-SEDATIVE MEDICINE FOR EXTERNAL USE</title><description>PROBLEM TO BE SOLVED: To obtain the subject medicine maintaining the percutaneous absorption property of indomethacin and improving the stability of indomethacin by including α-type crystal indomethacin. SOLUTION: This antiphlogistic-sedative medicine for external use contains indomethacin existing as α-type crystal in a base agent, for example, by a method comprising mixing an indomethacin suspension (prepared by homogeneously dispersing indomethacin, a water-soluble polymer, a moisturizing agent, a surfactant, an antiseptic, etc., in a solvent) with a water-soluble gel preferably in a weight ratio of 70:30 to 95:5. The indomethacin is preferably added usually in an amount of 1-40 wt.% to the above-described suspension or usually in an amount of 0.1-2 wt.% to the medicine. The water-soluble polymer is preferably added usually in an amount of 3-30 wt.% to the medicine.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1999</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB09AvxDPDw8Xf3DA7xdNYNdnVxDPEMc1XwdXXxdPb0c1Vw8w9ScI0IcQ3yc_RRCA125WFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8V4BHoaGhuaG5mYWjsbEqAEAb5Mm8w</recordid><startdate>19990629</startdate><enddate>19990629</enddate><creator>OTSUKI TOMOHIRO</creator><creator>YOSHINO YOSHIKO</creator><creator>KIUCHI CHIKAKO</creator><scope>EVB</scope></search><sort><creationdate>19990629</creationdate><title>ANTIPHLOGISTIC-SEDATIVE MEDICINE FOR EXTERNAL USE</title><author>OTSUKI TOMOHIRO ; YOSHINO YOSHIKO ; KIUCHI CHIKAKO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPH11171768A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1999</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>OTSUKI TOMOHIRO</creatorcontrib><creatorcontrib>YOSHINO YOSHIKO</creatorcontrib><creatorcontrib>KIUCHI CHIKAKO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OTSUKI TOMOHIRO</au><au>YOSHINO YOSHIKO</au><au>KIUCHI CHIKAKO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIPHLOGISTIC-SEDATIVE MEDICINE FOR EXTERNAL USE</title><date>1999-06-29</date><risdate>1999</risdate><abstract>PROBLEM TO BE SOLVED: To obtain the subject medicine maintaining the percutaneous absorption property of indomethacin and improving the stability of indomethacin by including α-type crystal indomethacin. SOLUTION: This antiphlogistic-sedative medicine for external use contains indomethacin existing as α-type crystal in a base agent, for example, by a method comprising mixing an indomethacin suspension (prepared by homogeneously dispersing indomethacin, a water-soluble polymer, a moisturizing agent, a surfactant, an antiseptic, etc., in a solvent) with a water-soluble gel preferably in a weight ratio of 70:30 to 95:5. The indomethacin is preferably added usually in an amount of 1-40 wt.% to the above-described suspension or usually in an amount of 0.1-2 wt.% to the medicine. The water-soluble polymer is preferably added usually in an amount of 3-30 wt.% to the medicine.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | ANTIPHLOGISTIC-SEDATIVE MEDICINE FOR EXTERNAL USE |
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