NEW COMPOUND

PROBLEM TO BE SOLVED: To provide a new compound consisting of a separated polypeptide containing an amino acid sequence having high identity to a specific amino acid sequence and useful e.g. for the treatment and diagnosis of hypercardia, cardiac failure, ischemia, arrhythmia, hypertension, atherosc...

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Hauptverfasser: HURLE MARK R, LEGER ISABELLE M, SOUCHET MICHEL L, CALMELS THIERRY PAUL GERARD, BRIL ANTOINE M A, TOURTELIER LAURENCE NATHALIE P
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creator HURLE MARK R
LEGER ISABELLE M
SOUCHET MICHEL L
CALMELS THIERRY PAUL GERARD
BRIL ANTOINE M A
TOURTELIER LAURENCE NATHALIE P
description PROBLEM TO BE SOLVED: To provide a new compound consisting of a separated polypeptide containing an amino acid sequence having high identity to a specific amino acid sequence and useful e.g. for the treatment and diagnosis of hypercardia, cardiac failure, ischemia, arrhythmia, hypertension, atherosclerosis, cancer, etc. SOLUTION: This new polypeptide is a separated polypeptide containing an amino acid sequence having identity of >=70% to the amino acid sequence of the formula I and a separated polypeptide containing an amino acid sequence having identity of >=70% to the amino acid sequence of the formula II. It is useful e.g. for the treatment and diagnostic assay of hypercardia, cardiac failure, ischemia, arrhythmia, hypertension, atherosclerosis, restenosis, chronic and acute inflammation, cerebral attack, rheumatoid arthritis, disseminated sclerosis, intestinal disease, diabetes, cancer, etc. The polypeptide can be produced from a cDNA library originated from mRNA in a cell such as human brain, heart or fetus dura cell by preparing a gene from the library by standard cloning and screening technique and expressing the gene in a host cell by recombination technique.
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It is useful e.g. for the treatment and diagnostic assay of hypercardia, cardiac failure, ischemia, arrhythmia, hypertension, atherosclerosis, restenosis, chronic and acute inflammation, cerebral attack, rheumatoid arthritis, disseminated sclerosis, intestinal disease, diabetes, cancer, etc. The polypeptide can be produced from a cDNA library originated from mRNA in a cell such as human brain, heart or fetus dura cell by preparing a gene from the library by standard cloning and screening technique and expressing the gene in a host cell by recombination technique.</description><edition>6</edition><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CALCULATING ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; COMPUTING ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; COUNTING ; CULTURE MEDIA ; ELECTRIC DIGITAL DATA PROCESSING ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19990427&amp;DB=EPODOC&amp;CC=JP&amp;NR=H11113583A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19990427&amp;DB=EPODOC&amp;CC=JP&amp;NR=H11113583A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HURLE MARK R</creatorcontrib><creatorcontrib>LEGER ISABELLE M</creatorcontrib><creatorcontrib>SOUCHET MICHEL L</creatorcontrib><creatorcontrib>CALMELS THIERRY PAUL GERARD</creatorcontrib><creatorcontrib>BRIL ANTOINE M A</creatorcontrib><creatorcontrib>TOURTELIER LAURENCE NATHALIE P</creatorcontrib><title>NEW COMPOUND</title><description>PROBLEM TO BE SOLVED: To provide a new compound consisting of a separated polypeptide containing an amino acid sequence having high identity to a specific amino acid sequence and useful e.g. for the treatment and diagnosis of hypercardia, cardiac failure, ischemia, arrhythmia, hypertension, atherosclerosis, cancer, etc. SOLUTION: This new polypeptide is a separated polypeptide containing an amino acid sequence having identity of &gt;=70% to the amino acid sequence of the formula I and a separated polypeptide containing an amino acid sequence having identity of &gt;=70% to the amino acid sequence of the formula II. 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LEGER ISABELLE M ; SOUCHET MICHEL L ; CALMELS THIERRY PAUL GERARD ; BRIL ANTOINE M A ; TOURTELIER LAURENCE NATHALIE P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPH11113583A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1999</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CALCULATING</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>COMPUTING</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>COUNTING</topic><topic>CULTURE MEDIA</topic><topic>ELECTRIC DIGITAL DATA PROCESSING</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>HURLE MARK R</creatorcontrib><creatorcontrib>LEGER ISABELLE M</creatorcontrib><creatorcontrib>SOUCHET MICHEL L</creatorcontrib><creatorcontrib>CALMELS THIERRY PAUL GERARD</creatorcontrib><creatorcontrib>BRIL ANTOINE M A</creatorcontrib><creatorcontrib>TOURTELIER LAURENCE NATHALIE P</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HURLE MARK R</au><au>LEGER ISABELLE M</au><au>SOUCHET MICHEL L</au><au>CALMELS THIERRY PAUL GERARD</au><au>BRIL ANTOINE M A</au><au>TOURTELIER LAURENCE NATHALIE P</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NEW COMPOUND</title><date>1999-04-27</date><risdate>1999</risdate><abstract>PROBLEM TO BE SOLVED: To provide a new compound consisting of a separated polypeptide containing an amino acid sequence having high identity to a specific amino acid sequence and useful e.g. for the treatment and diagnosis of hypercardia, cardiac failure, ischemia, arrhythmia, hypertension, atherosclerosis, cancer, etc. SOLUTION: This new polypeptide is a separated polypeptide containing an amino acid sequence having identity of &gt;=70% to the amino acid sequence of the formula I and a separated polypeptide containing an amino acid sequence having identity of &gt;=70% to the amino acid sequence of the formula II. It is useful e.g. for the treatment and diagnostic assay of hypercardia, cardiac failure, ischemia, arrhythmia, hypertension, atherosclerosis, restenosis, chronic and acute inflammation, cerebral attack, rheumatoid arthritis, disseminated sclerosis, intestinal disease, diabetes, cancer, etc. The polypeptide can be produced from a cDNA library originated from mRNA in a cell such as human brain, heart or fetus dura cell by preparing a gene from the library by standard cloning and screening technique and expressing the gene in a host cell by recombination technique.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CALCULATING
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
COMPUTING
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
COUNTING
CULTURE MEDIA
ELECTRIC DIGITAL DATA PROCESSING
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title NEW COMPOUND
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