RECOMBINANT MALASSEZIA ANTIGENIC PROTEIN AND ITS GENE

PROBLEM TO BE SOLVED: To obtain a new recombinant antigenic protein, comprising a peptide containing a specific amino acid sequence, having Malassezia allergenic activities and useful for diagnosis, treatment, prevention, etc., of Malassezia allergic diseases and Malassezia infectious diseases. SOLU...

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Bibliographische Detailangaben
Hauptverfasser:	DAIMON HISASHI, TAKESAKO KAZUTADA, KATOU IKUNOSHIN, AKIYAMA KAZUO, KURODA MASANOBU, YASUEDA HIROSHI, YAMAGUCHI HIDEYO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To obtain a new recombinant antigenic protein, comprising a peptide containing a specific amino acid sequence, having Malassezia allergenic activities and useful for diagnosis, treatment, prevention, etc., of Malassezia allergic diseases and Malassezia infectious diseases. SOLUTION: This new recombinant Malassezia antigenic protein is a peptide, comprising all or a part of an amino acid sequence described in the formula or a peptide containing the peptide and having Malassezia allergenic activities and is useful as a diagnostic agent, a therapeutic agent, a preventing agent, etc., for Malassezia allergic diseases and Malassezia infectious diseases. The antigenic protein is obtained by separating all the RNA from a microbial cell of a Malassezia furfur TIMM2782 strain, carrying out a reverse transcription polymerase chain reaction(RT PCR) with a primer capable of coding a part of the protein, cloning a cDNA of the Malassezia antigenic protein, then integrating the resultant DNA into a vector, preparing a recombinant DNA, transducing the resultant recombinant DNA into a host cell, transforming the host cell and culturing the prepared transformant.