PROTEIN AND ITS PRODUCTION

PROBLEM TO BE SOLVED: To obtain a new protein capable of efficiently bonding epithelial cell to a culturing vessel and proliferating the cell and useful for substrate, etc., for culture by extracting a bacterial cell surface protein from a bacterium belonging to the genus Lactobacillus by using a su...

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Bibliographische Detailangaben
Hauptverfasser:	KIMURA AKIRA, FUJIWARA SHIGERU, HASHIBA EN, SETO YASUYUKI
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To obtain a new protein capable of efficiently bonding epithelial cell to a culturing vessel and proliferating the cell and useful for substrate, etc., for culture by extracting a bacterial cell surface protein from a bacterium belonging to the genus Lactobacillus by using a surfactant, etc. SOLUTION: This new protein is derived from a bacterium belonging to the genus Lactobacillus and has cell adhesion activity and is capable of bonding a cell, especially an epithelial cell to a culturing vessel and proliferating the cell and is useful as a substrate for culture. The protein is obtained by extracting a bacterial cell surface protein from Lactobacillus acidophilus SBT 2062 strain (FERM P 10730), Lactobacillus gasseri SBT 2055 (FERM P 15535), Lactobacillus crispatus JCM 5808, Lactobacillus johnsonii SBT (FERM P-15534), etc., by using an alkali metal salt or a surfactant.