ORAL ADMINISTRATION AGENT HAVING REDUCING ACTION ON AIDS SYMPTOM

PROBLEM TO BE SOLVED: To obtain the subject agent by including a complex ingredient contained in a culture mycelium or a culture filtrate of Agaricus blazei Murr. as an active ingredient therein. SOLUTION: This agent contains a water-soluble complex ingredient contained in a culture mycelium or a culture filtrate of Kawariharatake (Agaricus blazei Murr.) which is mushroom of the genus Agaricus, commonly named Himematsutake. The complex ingredient contained in the culture mycelium obtained by carrying out the extraction treatment of the culture mycelium of the Himematsutake with hot water, then precipitating the extract with an alcohol and purifying the precipitated substance by chromatographic fractionation and/or separation with a membrane. The complex ingredient contained in the culture filtrate is prepared by performing the precipitating treatment of the culture filtrate of the Himamatsutake with the alcohol and then purifying the resultant precipitated substance by the chromatographic fractionation and/or separation with the membrane. The water-soluble complex ingredient has actions on remarkable reduction in AIDS symptoms by orally administering the ingredient to patients suffering from the AIDS and has no problem in acute and subacute toxicities.