ANTIBIOTIC BE-49589S AND THEIR PRODUCTION

PROBLEM TO BE SOLVED: To obtain the subject new compound excellent in antimicrobial activities against various pathogenic microorganisms including methicillin-resistant Staphylococcus aureus, useful as an antimicrobial agent for diseases resulting from these pathogenic microorganisms as causing micr...

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Bibliographische Detailangaben
Hauptverfasser:	HIRAYAMA MIOKO, TSUKAMOTO MASAHISA, NAKAJIMA SHIGERU, SUDA HIROYUKI, OJIRI KATSUHISA
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To obtain the subject new compound excellent in antimicrobial activities against various pathogenic microorganisms including methicillin-resistant Staphylococcus aureus, useful as an antimicrobial agent for diseases resulting from these pathogenic microorganisms as causing microorganisms. SOLUTION: This compound (salt) is shown by the formula [X1 and Y1 are bonded to form CO-O-CH2 or X1 is a group of the formula COOR1 (R1 is H or a lower alkyl) and Y1 is a group of the formula COOR2 (R2 is R1 ) or CH2 OH] such a compound in which X1 is COOH and Y1 is CH2 OH in the formula. The compound of the formula is obtained by culturing a bacterium (e.g. Microtetraspora sp. A 39,589 or its variant) belonging to the genus Microtetraspora, capable of producing the compound and collecting the compound from its culture solution or its cell when X1 and Y1 are bonded to form CO-O-CH2 or X1 is a group COOH and Y1 is COOH or CH2 OH.