PRODUCTION OF EPSILON-POLY-L-LYSINE

PROBLEM TO BE SOLVED: To obtain the subject compound useful for cosmetic, medicine, agrochemical, food additive, etc., by aerobically culturing a bacterium belonging to the genus Streptomyces, capable of fermentatively producing -poly-L-lysine in a medium having a specific residual carbon source con...

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Hauptverfasser: IWATA TOSHIHARU, ONCHI YUICHI, SHIRAISHI SHINJI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To obtain the subject compound useful for cosmetic, medicine, agrochemical, food additive, etc., by aerobically culturing a bacterium belonging to the genus Streptomyces, capable of fermentatively producing -poly-L-lysine in a medium having a specific residual carbon source concentration. SOLUTION: In a method for aerobically culturing a bacterium belonging to the genus Streptomyces, capable of fermentatively producing -poly-L-lysine [e.g. Streptomyces albulus lysinopolymerus B221021 strain (FERM P-15,193), etc.] in a medium and collecting -poly-L-lysine from the prepared culture solution, the residual carbon source concentration in a culture solution in an -poly- L-lysine production period is 1-50g/L to give the objective -poly-L-lysine high in safety and cation content, useful for toiletry, cosmetic, feed additive, medicine, agrochemical, food additive, electronic material, etc., in improved productivity.