PRODUCTION OF GLYCOSYL COMPOUND USING CYCLIC SILYL ETHER TYPE PROTECTING GROUP

PROBLEM TO BE SOLVED: To efficiently produce the subject compound by carrying out the glycosylating reaction of a saccharide derivative protected with a 1,1- disubstituted silylene group as a saccharide receptor and using a diol protecting group which is not eliminated at the time of reaction and can specifically be removed after the reaction. SOLUTION: A compound, protected with a 1,1-disubstituted silylene group and represented by formula I [R is a (substituted) 1-18C alkyl, a (substituted) cyclic 3-8C alkyl, a (substituted) aryl or a protected saccharide derivative; R and R are each a 1-6C alkyl or an aryl; A is CH(OH) or CHR CHR (either of R and R is OH and the other is H, OH, an acylamino, a protected saccharide derivative, etc.)] is reacted with a saccharide donor compound represented by the formula R X (R is a protected saccharide derivative having the bonded position at the anomer position; X is an eliminable group). Thereby, the diol protecting group which is not eliminated by the glcosylating reaction and can specifically be removed after the reaction is used to efficiently afford the objective glycosyl compound represented by formula II [A is CH(OR ), etc.].