HETEROCYCLIC ARYL-, ALKYL-, AND CYCLOALKYLACETAMIDE COMPOUNDS
Aryl-, cycloalkyl- and heterocyclyl-acetamides (I) and their salts are new. A = 6-10C aryl or 5-7 membered heteroaryl (contg. 1-3 S, N and/or O and opt. benz-fused) opt. mono-, di- or trisubstd. by halo, NO2, CN, CF3, OH, COOH or alkyl, alkoxy, acyl or alkoxycarbonyl with up to 8C; D = naphthyl, 3-6...
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Sprache: | eng |
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Zusammenfassung: | Aryl-, cycloalkyl- and heterocyclyl-acetamides (I) and their salts are new. A = 6-10C aryl or 5-7 membered heteroaryl (contg. 1-3 S, N and/or O and opt. benz-fused) opt. mono-, di- or trisubstd. by halo, NO2, CN, CF3, OH, COOH or alkyl, alkoxy, acyl or alkoxycarbonyl with up to 8C; D = naphthyl, 3-6C cycloalkyl or 4-6 membered opt. satd. or heterocyclyl (contg. 1-3 S, N and/or O and opt. benz-fused) opt. mono- or disubstd. by Q; Q = halo, CN, OH or alkyl or alkoxy with up to 4C; R =H; 3-10C cycloalkyl; 1-10C alkyl; or Ph opt. mono- or disubstd. by Q; R = H or 1-3C alkyl; R = H; 1-5C alkyl; benzyl; 3-7C cycloalkyl; or Ph or 5-7 membered heteroaryl (contg. 1-3 S, N and/or O atoms) opt. mono-, di- or trisubstd. by halo, NO2, Ph, OH or alkyl or alkoxy with up to 6C; R = H; -CH2OH; or -CH2O-CO-R ; and R = H; 1-8C alkyl; or Ph opt. mono-, di- or trisubstd. by Q. |
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