COMPOSITION FOR EXTERNAL USE IN SCALP

PURPOSE:To obtain a composition for external use in the scalp capable of manifesting ultrahigh suppressing effects on dandruff and pruritus and further excellent in persistence of the effects by using an antimicrobial agent used for the purpose of preventing the dandruff and pruritus with a keratinization improving agent. CONSTITUTION:This composition for external use in the scalp is obtained by using an antimicrobial agent which is a preventing agent for dandruff and pruritus and a keratinization improving agent comprising an amine derivative of formula I [R is a 4-40C straight-chain, branched chain or cyclic saturated or unsaturated hydrocarbon; R to R are each H or a 1-10C hydrocarbon (which can be substituted with OH)] or its acid addition salt in combination. An antimicrobial agent selected from a polyvalent metallic salt of 2- mercaptopyridine N-oxide, a 1-hydroxy-2-pyrrolidone derivative of formula II (R is an alkyl, an alkenyl, a cycloalkyl, etc.; R is H, an alkyl, an alkenyl, etc.; X is an organic salt group, a cation, etc.), 2,2'-dithio-bis-(pyridine N-oxide) of formula III and a benzalkonium salt of formula IV (R is a hydrocarbon; Y is an anion residue such as a phosphoric ester) is especially preferred as the antimicrobial agent.