2-BUSTITUTED-2-CYCLOALKENONE COMPOUNDS AND CARCINOSTATIC, OSTEOPLASY-STIMULATING AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT

PURPOSE:To provide a novel 2-substituted-2-cycloalkenone having pharmacological actions such as carcinostatic action and osteoplasy-stimulating action. CONSTITUTION:A compound of formula I [R is 1-10C aliphatic hydrocarbon group, 4-10C alicyclic hydrocarbon group, 6-10C aromatic hydrocarbon group, 1...

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Hauptverfasser: SUGIURA SATOSHI, HASATO ATSUO, TOMIMORI KOJI
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To provide a novel 2-substituted-2-cycloalkenone having pharmacological actions such as carcinostatic action and osteoplasy-stimulating action. CONSTITUTION:A compound of formula I [R is 1-10C aliphatic hydrocarbon group, 4-10C alicyclic hydrocarbon group, 6-10C aromatic hydrocarbon group, 1-9C heterocyclic group, which may be substututed; R is H, R ; R is H, 1-10C aliphatic hydrocarbon group which may be substituted; when B is H, A is OH, 2-7C acyloxy, 2-5C alkoxycarbonyloxy, 1-7C sulfonyloxy, or A and B together forms a bonding hand; G is groups of formula II to formula V (R , R are 1-10C aliphatic hydrocarbon group which may be substituted; R -R , R -R , R -R are H, 1-10C al iphatic hydrocarbon group which may be substituted); n is 0-2], e.g. 2-phenyl thio-6-[(3-methoxycarbonylmethoxyphenyl) hydroxymethyl]-2-cyclohexenone.