PHENANTHRENE DERIVATIVE OF LEUKOTRIENE ANTAGONISM

PURPOSE:To obtain a new compound useful as a therapeutic agent for diseases owing to leukotriene of pollinosis, bronchial asthma, arthritis, etc. CONSTITUTION:A compound of formula I (R1 is H or a 1-4C alkyl; R2 is H or methyl), e.g. a compound of formula II. The compound of formula II is obtained b...

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Hauptverfasser: IKEGAWA AKIKO, IKEGAWA TETSUO
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creator IKEGAWA AKIKO
IKEGAWA TETSUO
description PURPOSE:To obtain a new compound useful as a therapeutic agent for diseases owing to leukotriene of pollinosis, bronchial asthma, arthritis, etc. CONSTITUTION:A compound of formula I (R1 is H or a 1-4C alkyl; R2 is H or methyl), e.g. a compound of formula II. The compound of formula II is obtained by extracting RAIKOUTOU (root or leaf of Tripterygium wilfordii Hook. f.) which is a Chinese crude drug with a polar organic solvent such as methanol and purifying the extract by chromatography, etc.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHENANTHRENE DERIVATIVE OF LEUKOTRIENE ANTAGONISM
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