PHENANTHRENE DERIVATIVE OF LEUKOTRIENE ANTAGONISM

PHENANTHRENE DERIVATIVE OF LEUKOTRIENE ANTAGONISM

PURPOSE:To obtain a new compound useful as a therapeutic agent for diseases owing to leukotriene of pollinosis, bronchial asthma, arthritis, etc. CONSTITUTION:A compound of formula I (R1 is H or a 1-4C alkyl; R2 is H or methyl), e.g. a compound of formula II. The compound of formula II is obtained b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: IKEGAWA AKIKO, IKEGAWA TETSUO
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:PURPOSE:To obtain a new compound useful as a therapeutic agent for diseases owing to leukotriene of pollinosis, bronchial asthma, arthritis, etc. CONSTITUTION:A compound of formula I (R1 is H or a 1-4C alkyl; R2 is H or methyl), e.g. a compound of formula II. The compound of formula II is obtained by extracting RAIKOUTOU (root or leaf of Tripterygium wilfordii Hook. f.) which is a Chinese crude drug with a polar organic solvent such as methanol and purifying the extract by chromatography, etc.