COMPOSITION FOR TREATING AUTOIMMUNE HEMOLYTIC ANEMIA

PURPOSE:To obtain the subject multiple drug-resistant and safe composition, comprising carbamoyl-beta-D-ribofuranosyl-imidazolium-oleate as an active ingredient, capable of rapidly improving symptoms and reducing the weight of a steroidal agent used in combination and having low toxicity. CONSTITUTI...

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1. Verfasser: MORIMOTO IPPEI
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To obtain the subject multiple drug-resistant and safe composition, comprising carbamoyl-beta-D-ribofuranosyl-imidazolium-oleate as an active ingredient, capable of rapidly improving symptoms and reducing the weight of a steroidal agent used in combination and having low toxicity. CONSTITUTION:This composition comprises 4-carbamoyl-1-beta-D- ribofuranosylimidazolium-5-oleate (generic name: mizoribine) as an active ingredient. A commercially available pharmaceutical preparation of the mizoribine for oral administration is preferably simply used as the composition. The composition is preferably administered in a daily dose of 100-300mg at a time in 2-3 divided portions to an adult patient weighing 50-60kg by using a 25-mg or a 50-mg tablet of the pharmaceutical preparation of the mizoribine for the oral administration.