CEREBRAL FUNCTION IMPROVER COMPRISING SUCROSE ACRYL COMPOUND AS ACTIVE INGREDIENT
PURPOSE:To obtain a cerebral function improver having activating action on cholineacetyltransferase, comprising a sucrose acryl compound as an active ingredient. CONSTITUTION:This cerebral function improver comprises a compound of formula I [at least one of R1, R5 and R6 are an acyl of formula II or...
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| creator | IIZUKA SUSUMU YAMAGUCHI TAKUJI ISHIGE ATSUSHI IKETANI YUKINOBU |
| description | PURPOSE:To obtain a cerebral function improver having activating action on cholineacetyltransferase, comprising a sucrose acryl compound as an active ingredient. CONSTITUTION:This cerebral function improver comprises a compound of formula I [at least one of R1, R5 and R6 are an acyl of formula II or formula III (R9 to R14 are H, OH, a lower alkoxy or acetoxyl) and each of the others is acetyl, a lower alkoxy or H; R2 to R4, R7 and R8 each is H or acetyl] as an active ingredient. The compound of formula I is obtained by extraction and isolation from Lilium longiflorum, Lilium speciosum, Heloniopsis orientalis, Polygonum hydropiper, a Chirese crude medicine, Polygalae radix, a polygalaceous plant such as root of Polygala senega or a plant of the same genus. A cerebral function disorder such as cerebral infarction or dementia can be improved. The daily dose is 5-5,000mg/adult in the case of oral administration and 0.5-100mg/adult in the case of parenteral administration. |
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CONSTITUTION:This cerebral function improver comprises a compound of formula I [at least one of R1, R5 and R6 are an acyl of formula II or formula III (R9 to R14 are H, OH, a lower alkoxy or acetoxyl) and each of the others is acetyl, a lower alkoxy or H; R2 to R4, R7 and R8 each is H or acetyl] as an active ingredient. The compound of formula I is obtained by extraction and isolation from Lilium longiflorum, Lilium speciosum, Heloniopsis orientalis, Polygonum hydropiper, a Chirese crude medicine, Polygalae radix, a polygalaceous plant such as root of Polygala senega or a plant of the same genus. A cerebral function disorder such as cerebral infarction or dementia can be improved. The daily dose is 5-5,000mg/adult in the case of oral administration and 0.5-100mg/adult in the case of parenteral administration.</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950718&DB=EPODOC&CC=JP&NR=H07179348A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950718&DB=EPODOC&CC=JP&NR=H07179348A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>IIZUKA SUSUMU</creatorcontrib><creatorcontrib>YAMAGUCHI TAKUJI</creatorcontrib><creatorcontrib>ISHIGE ATSUSHI</creatorcontrib><creatorcontrib>IKETANI YUKINOBU</creatorcontrib><title>CEREBRAL FUNCTION IMPROVER COMPRISING SUCROSE ACRYL COMPOUND AS ACTIVE INGREDIENT</title><description>PURPOSE:To obtain a cerebral function improver having activating action on cholineacetyltransferase, comprising a sucrose acryl compound as an active ingredient. CONSTITUTION:This cerebral function improver comprises a compound of formula I [at least one of R1, R5 and R6 are an acyl of formula II or formula III (R9 to R14 are H, OH, a lower alkoxy or acetoxyl) and each of the others is acetyl, a lower alkoxy or H; R2 to R4, R7 and R8 each is H or acetyl] as an active ingredient. The compound of formula I is obtained by extraction and isolation from Lilium longiflorum, Lilium speciosum, Heloniopsis orientalis, Polygonum hydropiper, a Chirese crude medicine, Polygalae radix, a polygalaceous plant such as root of Polygala senega or a plant of the same genus. A cerebral function disorder such as cerebral infarction or dementia can be improved. The daily dose is 5-5,000mg/adult in the case of oral administration and 0.5-100mg/adult in the case of parenteral administration.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAh0dg1ydQpy9FFwC_VzDvH091Pw9A0I8g9zDVJw9geyPIM9_dwVgkOdg_yDXRUcnYMifcAS_qF-LgqOwUCREM8wVwWgoiBXF09XvxAeBta0xJziVF4ozc2g6OYa4uyhm1qQH59aXJCYnJqXWhLvFeBhYG5obmlsYuFoTIwaANuyL_o</recordid><startdate>19950718</startdate><enddate>19950718</enddate><creator>IIZUKA SUSUMU</creator><creator>YAMAGUCHI TAKUJI</creator><creator>ISHIGE ATSUSHI</creator><creator>IKETANI YUKINOBU</creator><scope>EVB</scope></search><sort><creationdate>19950718</creationdate><title>CEREBRAL FUNCTION IMPROVER COMPRISING SUCROSE ACRYL COMPOUND AS ACTIVE INGREDIENT</title><author>IIZUKA SUSUMU ; YAMAGUCHI TAKUJI ; ISHIGE ATSUSHI ; IKETANI YUKINOBU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPH07179348A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1995</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>IIZUKA SUSUMU</creatorcontrib><creatorcontrib>YAMAGUCHI TAKUJI</creatorcontrib><creatorcontrib>ISHIGE ATSUSHI</creatorcontrib><creatorcontrib>IKETANI YUKINOBU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>IIZUKA SUSUMU</au><au>YAMAGUCHI TAKUJI</au><au>ISHIGE ATSUSHI</au><au>IKETANI YUKINOBU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CEREBRAL FUNCTION IMPROVER COMPRISING SUCROSE ACRYL COMPOUND AS ACTIVE INGREDIENT</title><date>1995-07-18</date><risdate>1995</risdate><abstract>PURPOSE:To obtain a cerebral function improver having activating action on cholineacetyltransferase, comprising a sucrose acryl compound as an active ingredient. CONSTITUTION:This cerebral function improver comprises a compound of formula I [at least one of R1, R5 and R6 are an acyl of formula II or formula III (R9 to R14 are H, OH, a lower alkoxy or acetoxyl) and each of the others is acetyl, a lower alkoxy or H; R2 to R4, R7 and R8 each is H or acetyl] as an active ingredient. The compound of formula I is obtained by extraction and isolation from Lilium longiflorum, Lilium speciosum, Heloniopsis orientalis, Polygonum hydropiper, a Chirese crude medicine, Polygalae radix, a polygalaceous plant such as root of Polygala senega or a plant of the same genus. A cerebral function disorder such as cerebral infarction or dementia can be improved. The daily dose is 5-5,000mg/adult in the case of oral administration and 0.5-100mg/adult in the case of parenteral administration.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | CEREBRAL FUNCTION IMPROVER COMPRISING SUCROSE ACRYL COMPOUND AS ACTIVE INGREDIENT |
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