PRODUCTION OF 1-IODOALKYL CARBONATE ESTER

PURPOSE:To provide a safe and industrially satisfactory method for producing the 1-iodoalkyl carbonate ester useful for enhancing the oral absorbability of antibiotics in a high conversion and in a high yield. CONSTITUTION:A 1-halogenoalkyl carbonate ester is reacted with an iodination agent in the...

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Hauptverfasser:	KOMATSU TAKEKI, YAMANAKA MOTOSUKE, TSUKADA ITARU, NEGI SHIGETO, TSURUOKA AKIHIKO
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	PURPOSE:To provide a safe and industrially satisfactory method for producing the 1-iodoalkyl carbonate ester useful for enhancing the oral absorbability of antibiotics in a high conversion and in a high yield. CONSTITUTION:A 1-halogenoalkyl carbonate ester is reacted with an iodination agent in the presence of a quaternary ammonium salt or phosphonium salt in toluene to produce the 1-iodoalkyl carbonate ester.