METHOD FOR SELECTIVELY CRYSTALLIZING 2 HYDRATE AND 2.5 HYDRATE OF GUANOSINE MONOSODIUM SALT

PURPOSE:To provide a method for selectively crystallizing dihydrate of guanosine monosodium salt. CONSTITUTION:The characteristic of this method for selectively crystallizing dihydrate of guanosine monosodium salt comprises keeping pH of guanosine- containing solution to 11-14 and keeping the soluti...

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Hauptverfasser: IITANI KINZO, KUREYAMA MINEHIKO, MIYAZAWA TADASHI, TSUJITA HIROSHI, KANEKO TOYOICHI
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To provide a method for selectively crystallizing dihydrate of guanosine monosodium salt. CONSTITUTION:The characteristic of this method for selectively crystallizing dihydrate of guanosine monosodium salt comprises keeping pH of guanosine- containing solution to 11-14 and keeping the solution temperature to 40 deg.C to 90 deg.C or by keeping pH of guanosine-containing solution to 11-14 and keeping supersaturation degree at the start of crystallizing to 2-10. Since dihydrate of guanosine monosodium salt excellent in separating property and having high purification degree can be obtained thereby, guanylic acid can be industrially advantageously produced.