AZELASTINE EYE DROP COMPOSITION

PURPOSE:To obtain an azelastine-containing preparation for eye drop, having slight irritation, being stable as a preparation, having relatively alleviated bitterness. CONSTITUTION:An eye drop-composition contains (A) azelastine hydrochloride having excellent antiallergic action and (B) boric acid, glutamic acid or its salt contributing to alleviation of irritation and improvement in stability. The amounts of the components blended are 0.0005-2% (W/V) of the component A, 0.01-5.0(W/V)%, preferably 0.05-2.0% (W/V) of boric acid (salt) and 0.01-0.3% (W/V), preferably 0.05-0.25% (W/V) of glutamic acid (salt). The composition has preferably pH about 4.0-8.0, more preferably pH 5.0-7.0.