NEW DERMATAN SULFATE RELATED SUBSTANCE, INTERMEDIATE FOR SYNTHESIZING THE SAME, AND ITS PRODUCTION

PURPOSE:To chemically synthesize a hexasaccharide hexasulfate compd. expected to be useful as a blood coagulant by catalytically reducing a specific compd. or its salt. CONSTITUTION:A new hexasaccharide hexasulfate compd. of formula II is produced by catalytically reducing a compd. of formula I or i...

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Bibliographische Detailangaben
Hauptverfasser:	GOTO FUMITAKA, OGAWA TOMOYA, NAMIKAWA JUNICHI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	PURPOSE:To chemically synthesize a hexasaccharide hexasulfate compd. expected to be useful as a blood coagulant by catalytically reducing a specific compd. or its salt. CONSTITUTION:A new hexasaccharide hexasulfate compd. of formula II is produced by catalytically reducing a compd. of formula I or its salt. The resulting compd. has a structure formed by substituting terminal 2,5-anhydro- D-talitol 4-sulfate residues of a hexasaccharide hexasulfate compd. isolated from natural products with N-acetyl-D-galactosamine 4-sulfate residues and can be totally synthesized, thus enabling its production in a large amt. whereas only a minute amt. thereof has been isolated from natural products.