JPH0619349B

PURPOSE:To rapidly and simply perform the measurement of components in body fluids with high accuracy, by generating antigen antibody reaction by mixing a reagent and a specimen and calculating an agglutination ratio by a predetermined method while flowing the specimen solution. CONSTITUTION:Serum to be examined is diluted with a buffer solution while the diluted solution is mixed with a suspension of polystyrene latex to which the adhesion treatment of an antibody is applied and the resulting mixture is introduced into a reaction tank 5 with a thermostatic apparatus 4 and positive pressure is applied to a sheath tank 7 by a pump 17 through a pressure regulator 8 while said mixture is stirred through a motor 3 to supply the sheath solution and the agglutinated specimen solution to a detection pipe 1 under pressure. Particles are passed through the focus of condensed beam due to the cylindrical lens system 12 of beam from a semiconductor laser source 11 at a high speed in a state arranged into almost one line. Scattered beam by particles is received by a photodiode 16 through a beam blocking plate 15. The output thereof is applied to a microcomputer 26 through an amplifier 21, a limiter 22, an amplifier 23a, filter buffer and a discriminating circuit 25 to calculate an agglutination ratio. By this method, measurement of components in body fluids is performed rapidly and simply with high accuracy.