ARYL GROUP OR HETEROAROMATIC RING GROUP-SUBSTITUTED AMINOQUINOLONE DERIVATIVE AND AIDS THERAPEUTIC AGENT

PURPOSE:To provide the novel aminoquinolone derivative inhibiting the multiplication of HIV in a cell infected with the HIV and further suppressing the cell degeneration effect caused by the HIV. CONSTITUTION:The compound of formula I [X is H, halogen; Y is H, halogen, alkyl, amino, mono or dialkyl-substituted amino, etc.; Z is carboxy. 5-tetrazolyl; Q is N, CR (R is alkoxy. alkyl, H, etc.,); R is H, alkyl, aryl. five-six membered heteroaromatic single ring containing one or two of hetero atoms (N, O, S), etc.; R is group of formula II or formula III (R , R are aryl, heteroaromatic single ring containing one or two of N, 0 and S, etc.; R , R , R are H, alkyl; R is H, alkyl, OH, alkoxy; (n) is 1, 2; (m) is 0,1; (n') is 1,2; (n'') is 1-4)], e.g. 1-cyclopropyl-6-fluoro-8-difluoromethoxy-7-[4-(2-merthoxyphenyl) pipeazin-1-ly]-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hydrochloride.