ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE

(+)-N-(2-Ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene- 1,1-diamine can be prepared by reaction of 1-[(1-ethoxy)phenylamino]-1-methylthio-2-nitroethene with either racemic 1,2,2-trimethylpropargylamine and then subsequent chromatographic removal of the (+)-enantiomeric final pr...

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Hauptverfasser: RONARUDO EI JIYANISU, ETSUKEHARUTO NIIMAASU, AREKUSANDAA SUKURIABIN, YANNBERUNTO RENFUAASU, FUORUKAA MUSHIYAREKUURETEINA
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creator RONARUDO EI JIYANISU
ETSUKEHARUTO NIIMAASU
AREKUSANDAA SUKURIABIN
YANNBERUNTO RENFUAASU
FUORUKAA MUSHIYAREKUURETEINA
description (+)-N-(2-Ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene- 1,1-diamine can be prepared by reaction of 1-[(1-ethoxy)phenylamino]-1-methylthio-2-nitroethene with either racemic 1,2,2-trimethylpropargylamine and then subsequent chromatographic removal of the (+)-enantiomeric final product, or direct reaction with enantiomerically pure (1,2,2)-trimethylpropargylamine. The (+)-N-(2-ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene-1,1 -diamine can be used as an active compound in medicaments for the treatment of hypertension, cardiac arrhythmias, bronchial asthma or cerebral disorders.
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The (+)-N-(2-ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene-1,1 -diamine can be used as an active compound in medicaments for the treatment of hypertension, cardiac arrhythmias, bronchial asthma or cerebral disorders.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1993</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19930330&amp;DB=EPODOC&amp;CC=JP&amp;NR=H0578288A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19930330&amp;DB=EPODOC&amp;CC=JP&amp;NR=H0578288A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RONARUDO EI JIYANISU</creatorcontrib><creatorcontrib>ETSUKEHARUTO NIIMAASU</creatorcontrib><creatorcontrib>AREKUSANDAA SUKURIABIN</creatorcontrib><creatorcontrib>YANNBERUNTO RENFUAASU</creatorcontrib><creatorcontrib>FUORUKAA MUSHIYAREKUURETEINA</creatorcontrib><title>ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE</title><description>(+)-N-(2-Ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene- 1,1-diamine can be prepared by reaction of 1-[(1-ethoxy)phenylamino]-1-methylthio-2-nitroethene with either racemic 1,2,2-trimethylpropargylamine and then subsequent chromatographic removal of the (+)-enantiomeric final product, or direct reaction with enantiomerically pure (1,2,2)-trimethylpropargylamine. 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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE
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