ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE
(+)-N-(2-Ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene- 1,1-diamine can be prepared by reaction of 1-[(1-ethoxy)phenylamino]-1-methylthio-2-nitroethene with either racemic 1,2,2-trimethylpropargylamine and then subsequent chromatographic removal of the (+)-enantiomeric final pr...
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creator | RONARUDO EI JIYANISU ETSUKEHARUTO NIIMAASU AREKUSANDAA SUKURIABIN YANNBERUNTO RENFUAASU FUORUKAA MUSHIYAREKUURETEINA |
description | (+)-N-(2-Ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene- 1,1-diamine can be prepared by reaction of 1-[(1-ethoxy)phenylamino]-1-methylthio-2-nitroethene with either racemic 1,2,2-trimethylpropargylamine and then subsequent chromatographic removal of the (+)-enantiomeric final product, or direct reaction with enantiomerically pure (1,2,2)-trimethylpropargylamine. The (+)-N-(2-ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene-1,1 -diamine can be used as an active compound in medicaments for the treatment of hypertension, cardiac arrhythmias, bronchial asthma or cerebral disorders. |
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The (+)-N-(2-ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene-1,1 -diamine can be used as an active compound in medicaments for the treatment of hypertension, cardiac arrhythmias, bronchial asthma or cerebral disorders.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1993</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930330&DB=EPODOC&CC=JP&NR=H0578288A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930330&DB=EPODOC&CC=JP&NR=H0578288A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RONARUDO EI JIYANISU</creatorcontrib><creatorcontrib>ETSUKEHARUTO NIIMAASU</creatorcontrib><creatorcontrib>AREKUSANDAA SUKURIABIN</creatorcontrib><creatorcontrib>YANNBERUNTO RENFUAASU</creatorcontrib><creatorcontrib>FUORUKAA MUSHIYAREKUURETEINA</creatorcontrib><title>ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE</title><description>(+)-N-(2-Ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene- 1,1-diamine can be prepared by reaction of 1-[(1-ethoxy)phenylamino]-1-methylthio-2-nitroethene with either racemic 1,2,2-trimethylpropargylamine and then subsequent chromatographic removal of the (+)-enantiomeric final product, or direct reaction with enantiomerically pure (1,2,2)-trimethylpropargylamine. The (+)-N-(2-ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene-1,1 -diamine can be used as an active compound in medicaments for the treatment of hypertension, cardiac arrhythmias, bronchial asthma or cerebral disorders.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1993</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAhx9AvxdPEPcVXQ0NbU9dPVMNJ1DfHwj4gM8HD1i_QBCqnrahjqGOkY6YYEefoC5SJ9AoL8A0BSRrp-niFB_kAxVz9XXUMdQ10XT0dfTz9XHgbWtMSc4lReKM3NoODmGuLsoZtakB-fWlyQmJyal1oS7xXgYWBqbmFkYeFoTIQSACMmLrY</recordid><startdate>19930330</startdate><enddate>19930330</enddate><creator>RONARUDO EI JIYANISU</creator><creator>ETSUKEHARUTO NIIMAASU</creator><creator>AREKUSANDAA SUKURIABIN</creator><creator>YANNBERUNTO RENFUAASU</creator><creator>FUORUKAA MUSHIYAREKUURETEINA</creator><scope>EVB</scope></search><sort><creationdate>19930330</creationdate><title>ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE</title><author>RONARUDO EI JIYANISU ; ETSUKEHARUTO NIIMAASU ; AREKUSANDAA SUKURIABIN ; YANNBERUNTO RENFUAASU ; FUORUKAA MUSHIYAREKUURETEINA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPH0578288A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1993</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RONARUDO EI JIYANISU</creatorcontrib><creatorcontrib>ETSUKEHARUTO NIIMAASU</creatorcontrib><creatorcontrib>AREKUSANDAA SUKURIABIN</creatorcontrib><creatorcontrib>YANNBERUNTO RENFUAASU</creatorcontrib><creatorcontrib>FUORUKAA MUSHIYAREKUURETEINA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RONARUDO EI JIYANISU</au><au>ETSUKEHARUTO NIIMAASU</au><au>AREKUSANDAA SUKURIABIN</au><au>YANNBERUNTO RENFUAASU</au><au>FUORUKAA MUSHIYAREKUURETEINA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE</title><date>1993-03-30</date><risdate>1993</risdate><abstract>(+)-N-(2-Ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene- 1,1-diamine can be prepared by reaction of 1-[(1-ethoxy)phenylamino]-1-methylthio-2-nitroethene with either racemic 1,2,2-trimethylpropargylamine and then subsequent chromatographic removal of the (+)-enantiomeric final product, or direct reaction with enantiomerically pure (1,2,2)-trimethylpropargylamine. The (+)-N-(2-ethoxyphenyl)-N',N'-(1,2,2-trimethylpropyl)-2-nitroethene-1,1 -diamine can be used as an active compound in medicaments for the treatment of hypertension, cardiac arrhythmias, bronchial asthma or cerebral disorders.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | ANTIDOTE (+)-N-(2-ETHOXYPHENYL)-N'-(1,2,2-TRIMETHYLPROPYL)-2-NITROETHENE-1,1-DIAMINE |
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