JPH0576480B

JPH0576480B

NEW MATERIAL:A compound expressed by formula I (Y is =CH- or N; R is lower alkyl). EXAMPLE:7beta-[2-(2-Aminothiazol-4-yl)-2-(Z)-methoxyiminoacetami-do]-3 -(1-morpho lino[4,3-b]pyrazolio)methyl-3-cephem-4-car-boxy-late expressed by formula II. USE:An antimicrobial agent against Gram-positive and Gram...

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Bibliographische Detailangaben
Hauptverfasser: MACHIDA YOSHIMASA, YAMAUCHI HIROSHI, KAMYA TAKU, NOMOTO SEIICHIRO, SUGYAMA ISAO, SAITO ISAO, NEGI SHIGETO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:NEW MATERIAL:A compound expressed by formula I (Y is =CH- or N; R is lower alkyl). EXAMPLE:7beta-[2-(2-Aminothiazol-4-yl)-2-(Z)-methoxyiminoacetami-do]-3 -(1-morpho lino[4,3-b]pyrazolio)methyl-3-cephem-4-car-boxy-late expressed by formula II. USE:An antimicrobial agent against Gram-positive and Gram-negative bacteria. PREPARATION:A compound expressed by formula III, a compound having the protected functional group thereof or a salt thereof, e.g. 7beta-[2-(2- aminothiazol-4-yl )-2-( Z )-methoxyiminoacetamido]-3-acetoxymethyl-3-cephem-4- carboxylic acid, is reacted with morpholino[4,3-b]pyrazole expressed by formula IV.