JPH0551581B

JPH0551581B

Pyridinecarboxylic acid esters of the formula (I) in which R is an optionally substituted aryl or heterocyclic radical, R1 and R2 are hydrogen, alkyl, aryl, aralkyl, acyloxyalkyl or hydroxyalkyl, or R1 with X forms a carbonyl-containing heterocyclic ring, X is -CN, -CO-R4, -COOR5 or -SO2R6, R4, R5 a...

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Hauptverfasser: URURITSUHI BENTSU, EKUBERUTO BEEINGAA, HORUSUTO MAIYAA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Pyridinecarboxylic acid esters of the formula (I) in which R is an optionally substituted aryl or heterocyclic radical, R1 and R2 are hydrogen, alkyl, aryl, aralkyl, acyloxyalkyl or hydroxyalkyl, or R1 with X forms a carbonyl-containing heterocyclic ring, X is -CN, -CO-R4, -COOR5 or -SO2R6, R4, R5 and R6 are various optionally substituted radicals, and R3 is different from R5 and is a substituted or interrupted hydrocarbon radical, or pharmaceutically acceptable salts thereof control the otherwise negative effects of ischaemia and/or hypoxia.