JPH05244977

A method for activating recombinant proteins which are in an at least partially inactive form, in which solubilisation and/or renaturation techniques known per se are used to activate a protein which contains at its N and/or C terminus additional helper sequences with a length of 2 to 50 amino acids...

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Hauptverfasser: KAROORA DONII, DOROTEA ANBUROJIUSU, RAINAA RUUDORUFU
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method for activating recombinant proteins which are in an at least partially inactive form, in which solubilisation and/or renaturation techniques known per se are used to activate a protein which contains at its N and/or C terminus additional helper sequences with a length of 2 to 50 amino acids, where the relative hydrophobicities of these helper sequences, calculated as the total of the relative hydrophobicities, indicated in Table 1, of the individual amino acids, have a negative numerical value.