TECHNETIUM- AND RENIUM-CHELATE, DIAGNOSTIC AGENT CONTAINING SAME, MEDICINE CONTAINING SAME FOR THERAPY OF TUMOR, AND PREPARATION THEREOF

Compounds of the general formula I are capable of reducing pertechnetate to an oxidation level of less than +7 without an addition of reducing agents, forming, via the groups Y and Z, stable complexes with the technetium or rhenium isotopes which have been reduced in this manner, and, if appropriate...

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Hauptverfasser: SHIYUTEFUAN RUTSUPUREHITO, BUORUFUGANGU KURANPU, RAINHARUTO NOIMAIAA, ETSUKEHARUTO HAAN
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creator SHIYUTEFUAN RUTSUPUREHITO
BUORUFUGANGU KURANPU
RAINHARUTO NOIMAIAA
ETSUKEHARUTO HAAN
description Compounds of the general formula I are capable of reducing pertechnetate to an oxidation level of less than +7 without an addition of reducing agents, forming, via the groups Y and Z, stable complexes with the technetium or rhenium isotopes which have been reduced in this manner, and, if appropriate, accumulating selectively in certain tissues or lesions due to a compound which is coupled with the aid of a functional group which is part of R . The technetium and rhenium complexes of the compounds of the general formula I, and their salts with organic and inorganic acids, can be employed in in-vivo diagnostics and in therapy, preferably in tumour therapy.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TECHNETIUM- AND RENIUM-CHELATE, DIAGNOSTIC AGENT CONTAINING SAME, MEDICINE CONTAINING SAME FOR THERAPY OF TUMOR, AND PREPARATION THEREOF
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