TECHNETIUM- AND RENIUM-CHELATE, DIAGNOSTIC AGENT CONTAINING SAME, MEDICINE CONTAINING SAME FOR THERAPY OF TUMOR, AND PREPARATION THEREOF

Compounds of the general formula I are capable of reducing pertechnetate to an oxidation level of less than +7 without an addition of reducing agents, forming, via the groups Y and Z, stable complexes with the technetium or rhenium isotopes which have been reduced in this manner, and, if appropriate...

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Bibliographische Detailangaben
Hauptverfasser:	SHIYUTEFUAN RUTSUPUREHITO, BUORUFUGANGU KURANPU, RAINHARUTO NOIMAIAA, ETSUKEHARUTO HAAN
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of the general formula I are capable of reducing pertechnetate to an oxidation level of less than +7 without an addition of reducing agents, forming, via the groups Y and Z, stable complexes with the technetium or rhenium isotopes which have been reduced in this manner, and, if appropriate, accumulating selectively in certain tissues or lesions due to a compound which is coupled with the aid of a functional group which is part of R . The technetium and rhenium complexes of the compounds of the general formula I, and their salts with organic and inorganic acids, can be employed in in-vivo diagnostics and in therapy, preferably in tumour therapy.