COMPOUND COMPOSITION

PURPOSE:To prepare a compound composition of bromohexine chloride substantially not causing the adsorption of the bromohexine chloride on plastic packaging materials or containers when packaged and stored by mixing the bromohexine chloride with crystal cellulose and a specific amount of a solvent, k...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OKAMOTO AKIHIKO, KUKITA TAKUYA, YAMAGUCHI AKIYOSHI, NEMOTO MASAMI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PURPOSE:To prepare a compound composition of bromohexine chloride substantially not causing the adsorption of the bromohexine chloride on plastic packaging materials or containers when packaged and stored by mixing the bromohexine chloride with crystal cellulose and a specific amount of a solvent, kneading the mixture, drying, etc. CONSTITUTION:Bromohexine chloride, crystal cellulose and a solvent capable of dissolving >= 90% of the bromohexine chloride (e.g. water, methanol or ethanol) are mixed in an arbitrary order, kneaded and dried. Or the bromohexine is mixed with the crystal cellulose powder and subsequently ground until the bromohexine chloride is converted into an amorphous state.