DI(NITROXYALKYL)AMIDE OF PYRIDINE-2,4-AND 2,5-DICARBOXYLIC ACID, AND PREPARATION AND USE THEREOF

The pyridine-2,4- and 2,5-dicarboxylic acid di(nitroxyalkyl)amides and their salts have formula (I). R = 1-4C alkylene. (I), where R is methylene, propylene or butylene, are new compounds. (I) are administered orally, especially in doses of 0.01-5.0 mg/kg.day, or parenterally, especially in doses of...

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Sprache:eng
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Zusammenfassung:The pyridine-2,4- and 2,5-dicarboxylic acid di(nitroxyalkyl)amides and their salts have formula (I). R = 1-4C alkylene. (I), where R is methylene, propylene or butylene, are new compounds. (I) are administered orally, especially in doses of 0.01-5.0 mg/kg.day, or parenterally, especially in doses of 0.005-1.0 mg/kg/day. Rectal application may also be used.