ANTI-ALLERGIC AGENT FOR LOCALLY ADMINISTERING TO MUCOSA

PURPOSE:To provide the subject safe administration agent containing both isothipendyl and an anti-inflammatory agent or angiotonic, exhibiting an excellent and strong anti-allergic action and an extremely little mucosa-irritating property, and useful for the mucosas of eyes and noses in a fine administration amount. CONSTITUTION:An anti-allergic agent for administering to mucosas, capable of improving the allergic syndromes of the mucosas of eyes or noses in a smaller administration amount than those of oral drugs contains isothipendyl, i.e. 10-(2-dimethylaminopropyl)10H-pyrido[3,2-b][1,4] benzothiazine or a salt thereof (having a strong anti-histaminic action and a strong anti-allergic action and useful as an oral drug or external dermal administration agent) and at least one of angiotonics such as glycyrrhizic acid dipotassium salt or lysozyme chloride or a angiotonic such as naphazoline hydrochloride or epinephrine preferably in a weight ratio of approximately 0.01-5.0 based on the total amount in a case of the anti-inflammatory agent or in a weight ratio of approximately 0.001-0.05 in a case of the angiotonic.