STEROID OINTMENT

PURPOSE:To obtain an ointment having excellent transcutaneous absorbability and low irritation by compounding a steroidal antiinflammatory agent in combination with a triglyceride and/or a lactic acid ester in an oily ointment base. CONSTITUTION:The objective ointment can be prepared by compounding...

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Bibliographische Detailangaben
Hauptverfasser: KOYAMA SAWAKO, KAIHO FUSAO, WATANABE EIJI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PURPOSE:To obtain an ointment having excellent transcutaneous absorbability and low irritation by compounding a steroidal antiinflammatory agent in combination with a triglyceride and/or a lactic acid ester in an oily ointment base. CONSTITUTION:The objective ointment can be prepared by compounding an oily ointment base with (A) 0.01-2.00wt.% (preferably 0.02-1.00wt.%) of a steroidal antiinflammatory agent such as prednisolone, hydrocortisone, dexamethasone and triamcinolone acetonide (especially preferably dexamethasone acetate) and (B) 0.5-20wt.% (preferably 5-15wt.%) of a 6-12C medium-chain fatty acid triglyceride (preferably straight-chain saturated fatty acid triglyceride) and/or 0.1-20wt.% (preferably 0.5-5wt.%) of a lactic acid ester of a 12-18C aliphatic alcohol (preferably cetyl lactate).