TABLET AND GRANULE

PURPOSE:To provide a tablet or granule capable of readily polished, having a new glassy luster, free from the anxiety about remained solvents, capable of being applied even to thermally unstable drugs and having a beautiful appearance and a high commercial value. CONSTITUTION:A tablet or granule, especially the tablet or granule coated with a coating soluble in a gastric juice or intestinal juice or with a sustained- release coating, is coated with a chitosan solution to provide the tablet or granule having the above-mentioned effects. The coating solution is prepared by dissolving the chitosan in diluted acetic acid or sulfuric acid. The concentration of the chitosan depends on the polymerization degree of the chitosan, but is suitably approximately 0.1-3.0wt.%. The solution is, if necessary, changed into an organic solvent solution such as a water-alcohol solution. The coating amount is usually 0.01-3.0wt.%, preferably 0.01-1.0wt.%.