READILY DISINTEGRABLE PANCREATIN GRANULE

PURPOSE:To obtain the title granules causing no prolonged disintegration time thereof due to its hardening by incorporating fine silicon dioxide powder in an aqueous binder solution or water as kneading liquid. CONSTITUTION:A mixture comprising, based on the final granules, (A) 40-90wt.% of pancreat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KOKUBO HIROYASU, MUTO YASUAKI, MINEMURA KATSUYOSHI, ARAUME KIYOSHI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PURPOSE:To obtain the title granules causing no prolonged disintegration time thereof due to its hardening by incorporating fine silicon dioxide powder in an aqueous binder solution or water as kneading liquid. CONSTITUTION:A mixture comprising, based on the final granules, (A) 40-90wt.% of pancreatin, (B) a shaping agent such as lactose or starch, (C)