COMPLEXATION FOR REMOVAL OF HEAVY METAL FROM AQUEOUS SOLUTION AND FOR ANALYSIS THEREOF AND MONOCLONAL ANTIBODY AGAINST NON-COMPLEXING COMPLEX FORMING AGENT

The invention relates to monoclonal antibodies (MAbs) which bind with high specificity and avidity to water-soluble complexones such as ethylenediaminetetraacetate (EDTA) or diethylenetriaminepentaacetate (DTPA) and after complexation of EDTA or DTPA with metal ions retain their high avidity and spe...

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Bibliographische Detailangaben
Hauptverfasser: KURAUSU BOSHIYURETSUTO, GERUHARUTO JIIMAN, PEETAA HERUMENCHIN
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to monoclonal antibodies (MAbs) which bind with high specificity and avidity to water-soluble complexones such as ethylenediaminetetraacetate (EDTA) or diethylenetriaminepentaacetate (DTPA) and after complexation of EDTA or DTPA with metal ions retain their high avidity and specificity for these complexones. These MAbs can therefore be used, for example coupled to filters or other supports, for removing toxic heavy metals which are complexed with EDTA or DTPA. Furthermore, these MAbs are suitable as components of immunoassays (RIA, ELISA etc.) for the quantitative detection of EDTA and DTPA in aqueous solutions.