PRODUCTION OF BROMOFLUOROBENZENES
PURPOSE:To sufficiently advance denitrating and brominating reactions and industrially and advantageously produce bromofluorobenzenes by reacting fluoronitrobenzenes with bromine gas under prescribed conditions. CONSTITUTION:Fluoronitrobenzenes (e.g. 2,4-difluoronitrobenzene) are reacted with bromin...
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Zusammenfassung: | PURPOSE:To sufficiently advance denitrating and brominating reactions and industrially and advantageously produce bromofluorobenzenes by reacting fluoronitrobenzenes with bromine gas under prescribed conditions. CONSTITUTION:Fluoronitrobenzenes (e.g. 2,4-difluoronitrobenzene) are reacted with bromine gas in the vapor phase at 250-400 deg.C to afford bromofluorobenzenes (e.g. 1-bromo-2,4-difluorobenzene). A high yield can be attained by the aforementioned method. The bromofluorobenzenes are useful as an intermediate for medicines, agricultural chemicals, etc. |
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