ANTIBIOTIC SUBSTANCE GALACARDINS A AND B
PURPOSE:To obtain an antimicrobial agent for infectious diseases caused by Gram-positive bacteria by culturing a microorganism, belonging to actinomyces and capable of producing galacardins A (G-A) and B (G-B). CONSTITUTION:An antibiotic substance galacardin A produced by culturing a strain SANK 642...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | INUKAI MASATOSHI TAKEUCHI MICHIKO ENOKIDA RYUZO KAGASAKI TAKESHI NAGAKI HIDEMI TAKAHASHI HIDEJI |
| description | PURPOSE:To obtain an antimicrobial agent for infectious diseases caused by Gram-positive bacteria by culturing a microorganism, belonging to actinomyces and capable of producing galacardins A (G-A) and B (G-B). CONSTITUTION:An antibiotic substance galacardin A produced by culturing a strain SANK 64289 (FERM P-10940) in a culture medium containing glucose, etc., providing a culture, centrifuging and purifying the resultant culture and having the following physico-chemical properties. Properties of the substance; amphoteric water-soluble white powder. Specific rotatory power [alpha]-38.7 deg. (c, 1.00, H2O). Elementary analysis value%; C, 50.55; H, 5.62; N, 5.06; Cl, 2.39; F, 1.16 (provided that trifluoroacetic acid and water are partially contained). Molecular formula; C101H121O46N9Cl2. Molecular weight; 2265 (measured by an FAB- MAS method). Hydrolysis; producing monodechlorovancomycinic acid, etc., as amino acids by acid hydrolysis. Ultraviolet absorption spectrum; lambdamaxnm (E) 280nm (39.6). Soluble in water, methanol, etc. The galacardin B is similarly produced. The resultant G-A and G-B, as necessary, contained to produce an antimicrobial agent. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JPH0383594A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JPH0383594A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JPH0383594A3</originalsourceid><addsrcrecordid>eNrjZNBw9AvxdPL0D_F0VggOdQoOcfRzdlVwd_RxdHYMcvH0C1ZwVHD0c1Fw4mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8V4BHgbGFsamliaOxkQoAQCoCyOM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ANTIBIOTIC SUBSTANCE GALACARDINS A AND B</title><source>esp@cenet</source><creator>INUKAI MASATOSHI ; TAKEUCHI MICHIKO ; ENOKIDA RYUZO ; KAGASAKI TAKESHI ; NAGAKI HIDEMI ; TAKAHASHI HIDEJI</creator><creatorcontrib>INUKAI MASATOSHI ; TAKEUCHI MICHIKO ; ENOKIDA RYUZO ; KAGASAKI TAKESHI ; NAGAKI HIDEMI ; TAKAHASHI HIDEJI</creatorcontrib><description>PURPOSE:To obtain an antimicrobial agent for infectious diseases caused by Gram-positive bacteria by culturing a microorganism, belonging to actinomyces and capable of producing galacardins A (G-A) and B (G-B). CONSTITUTION:An antibiotic substance galacardin A produced by culturing a strain SANK 64289 (FERM P-10940) in a culture medium containing glucose, etc., providing a culture, centrifuging and purifying the resultant culture and having the following physico-chemical properties. Properties of the substance; amphoteric water-soluble white powder. Specific rotatory power [alpha]-38.7 deg. (c, 1.00, H2O). Elementary analysis value%; C, 50.55; H, 5.62; N, 5.06; Cl, 2.39; F, 1.16 (provided that trifluoroacetic acid and water are partially contained). Molecular formula; C101H121O46N9Cl2. Molecular weight; 2265 (measured by an FAB- MAS method). Hydrolysis; producing monodechlorovancomycinic acid, etc., as amino acids by acid hydrolysis. Ultraviolet absorption spectrum; lambdamaxnm (E) 280nm (39.6). Soluble in water, methanol, etc. The galacardin B is similarly produced. The resultant G-A and G-B, as necessary, contained to produce an antimicrobial agent.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1991</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19910409&DB=EPODOC&CC=JP&NR=H0383594A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19910409&DB=EPODOC&CC=JP&NR=H0383594A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>INUKAI MASATOSHI</creatorcontrib><creatorcontrib>TAKEUCHI MICHIKO</creatorcontrib><creatorcontrib>ENOKIDA RYUZO</creatorcontrib><creatorcontrib>KAGASAKI TAKESHI</creatorcontrib><creatorcontrib>NAGAKI HIDEMI</creatorcontrib><creatorcontrib>TAKAHASHI HIDEJI</creatorcontrib><title>ANTIBIOTIC SUBSTANCE GALACARDINS A AND B</title><description>PURPOSE:To obtain an antimicrobial agent for infectious diseases caused by Gram-positive bacteria by culturing a microorganism, belonging to actinomyces and capable of producing galacardins A (G-A) and B (G-B). CONSTITUTION:An antibiotic substance galacardin A produced by culturing a strain SANK 64289 (FERM P-10940) in a culture medium containing glucose, etc., providing a culture, centrifuging and purifying the resultant culture and having the following physico-chemical properties. Properties of the substance; amphoteric water-soluble white powder. Specific rotatory power [alpha]-38.7 deg. (c, 1.00, H2O). Elementary analysis value%; C, 50.55; H, 5.62; N, 5.06; Cl, 2.39; F, 1.16 (provided that trifluoroacetic acid and water are partially contained). Molecular formula; C101H121O46N9Cl2. Molecular weight; 2265 (measured by an FAB- MAS method). Hydrolysis; producing monodechlorovancomycinic acid, etc., as amino acids by acid hydrolysis. Ultraviolet absorption spectrum; lambdamaxnm (E) 280nm (39.6). Soluble in water, methanol, etc. The galacardin B is similarly produced. The resultant G-A and G-B, as necessary, contained to produce an antimicrobial agent.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1991</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBw9AvxdPL0D_F0VggOdQoOcfRzdlVwd_RxdHYMcvH0C1ZwVHD0c1Fw4mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8V4BHgbGFsamliaOxkQoAQCoCyOM</recordid><startdate>19910409</startdate><enddate>19910409</enddate><creator>INUKAI MASATOSHI</creator><creator>TAKEUCHI MICHIKO</creator><creator>ENOKIDA RYUZO</creator><creator>KAGASAKI TAKESHI</creator><creator>NAGAKI HIDEMI</creator><creator>TAKAHASHI HIDEJI</creator><scope>EVB</scope></search><sort><creationdate>19910409</creationdate><title>ANTIBIOTIC SUBSTANCE GALACARDINS A AND B</title><author>INUKAI MASATOSHI ; TAKEUCHI MICHIKO ; ENOKIDA RYUZO ; KAGASAKI TAKESHI ; NAGAKI HIDEMI ; TAKAHASHI HIDEJI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPH0383594A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1991</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>INUKAI MASATOSHI</creatorcontrib><creatorcontrib>TAKEUCHI MICHIKO</creatorcontrib><creatorcontrib>ENOKIDA RYUZO</creatorcontrib><creatorcontrib>KAGASAKI TAKESHI</creatorcontrib><creatorcontrib>NAGAKI HIDEMI</creatorcontrib><creatorcontrib>TAKAHASHI HIDEJI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>INUKAI MASATOSHI</au><au>TAKEUCHI MICHIKO</au><au>ENOKIDA RYUZO</au><au>KAGASAKI TAKESHI</au><au>NAGAKI HIDEMI</au><au>TAKAHASHI HIDEJI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIBIOTIC SUBSTANCE GALACARDINS A AND B</title><date>1991-04-09</date><risdate>1991</risdate><abstract>PURPOSE:To obtain an antimicrobial agent for infectious diseases caused by Gram-positive bacteria by culturing a microorganism, belonging to actinomyces and capable of producing galacardins A (G-A) and B (G-B). CONSTITUTION:An antibiotic substance galacardin A produced by culturing a strain SANK 64289 (FERM P-10940) in a culture medium containing glucose, etc., providing a culture, centrifuging and purifying the resultant culture and having the following physico-chemical properties. Properties of the substance; amphoteric water-soluble white powder. Specific rotatory power [alpha]-38.7 deg. (c, 1.00, H2O). Elementary analysis value%; C, 50.55; H, 5.62; N, 5.06; Cl, 2.39; F, 1.16 (provided that trifluoroacetic acid and water are partially contained). Molecular formula; C101H121O46N9Cl2. Molecular weight; 2265 (measured by an FAB- MAS method). Hydrolysis; producing monodechlorovancomycinic acid, etc., as amino acids by acid hydrolysis. Ultraviolet absorption spectrum; lambdamaxnm (E) 280nm (39.6). Soluble in water, methanol, etc. The galacardin B is similarly produced. The resultant G-A and G-B, as necessary, contained to produce an antimicrobial agent.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_JPH0383594A |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | ANTIBIOTIC SUBSTANCE GALACARDINS A AND B |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T07%3A32%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=INUKAI%20MASATOSHI&rft.date=1991-04-09&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EJPH0383594A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |